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Target
Melanocortin receptor 3
Ligand
BDBM50250201
Substrate
n/a
Meas. Tech.
ChEBML_1681317
EC50
19±n/a nM
Citation
 Palmer, D; Gonçalves, JPL; V Hansen, L; Wu, B; Hald, H; Schoffelen, S; Diness, F; Le Quement, ST; Nielsen, TE; Meldal, M Click-Chemistry-Mediated Synthesis of Selective Melanocortin Receptor 4 Agonists. J Med Chem 60:8716-8730 (2017) [PubMed]  Article 
Target
Name:
Melanocortin receptor 3
Synonyms:
MC3-R | MC3R | MC3R_HUMAN | Melanocortin MC3 | Melanocortin receptor (M3 and M4)
Type:
Enzyme
Mol. Mass.:
36044.86
Organism:
Homo sapiens (Human)
Description:
P41968
Residue:
323
Sequence:
MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
  
Inhibitor
Name:
BDBM50250201
Synonyms:
CHEMBL4070639
Type:
Small organic molecule
Emp. Form.:
C48H63N17O9S
Mol. Mass.:
1054.187
SMILES:
CSCC[C@H](NC(=O)[C@@H]1Cc2cn(C[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N1)nn2)C(O)=O |r|
Structure:
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