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Target
Ornithine decarboxylase
Ligand
BDBM50005719
Substrate
n/a
Meas. Tech.
ChEBML_148124
IC50
35±n/a nM
Citation
 Stanek, J; Frei, J; Mett, H; Schneider, P; Regenass, U 2-substituted 3-(aminooxy)propanamines as inhibitors of ornithine decarboxylase: synthesis and biological activity. J Med Chem 35:1339-44 (1992) [PubMed]  Article 
Target
Name:
Ornithine decarboxylase
Synonyms:
DCOR_RAT | Odc | Odc1
Type:
PROTEIN
Mol. Mass.:
51037.04
Organism:
Rattus norvegicus
Description:
ChEMBL_1344641
Residue:
461
Sequence:
MGSFTKEEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDVLKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPPERIIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMGTEVGFSMYLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQTGSDDEDESNEQTLMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCSLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRSMWQLMKQIQSHGFPPEVEEQDVGTLPMSCAQESGMDRHPAACASASINV
  
Inhibitor
Name:
BDBM50005719
Synonyms:
(APA)O-(3-Amino-propyl)-hydroxylamine | 3-AMINOOXY-1-AMINOPROPANE | CHEMBL1209776 | CHEMBL281021
Type:
Small organic molecule
Emp. Form.:
C3H10N2O
Mol. Mass.:
90.1243
SMILES:
NCCCON
Structure:
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