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Target
Aspartyl aminopeptidase
Ligand
BDBM50008434
Substrate
n/a
Meas. Tech.
ChEMBL_32822 (CHEMBL646473)
Ki
57000.0±n/a nM
Citation
 Ocain, TD; Rich, DH alpha-Keto amide inhibitors of aminopeptidases. J Med Chem 35:451-6 (1992) [PubMed]  Article 
Target
Name:
Aspartyl aminopeptidase
Synonyms:
ASPEP | Aminopeptidase | Aspartyl aminopeptidase | DAP | DNPEP | DNPEP_HUMAN
Type:
PROTEIN
Mol. Mass.:
52436.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_32822
Residue:
475
Sequence:
MQVAMNGKARKEAVQTAAKELLKFVNRSPSPFHAVAECRNRLLQAGFSELKETEKWNIKPESKYFMTRNSSTIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRRSRRSQVGFQQVGVETYGGGIWSTWFDRDLTLAGRVIVKCPTSGRLEQQLVHVERPILRIPHLAIHLQRNINENFGPNTEMHLVPILATAIQEELEKGTPEPGPLNAVDERHHSVLMSLLCAHLGLSPKDIVEMELCLADTQPAVLGGAYDEFIFAPRLDNLHSCFCALQALIDSCAGPGSLATEPHVRMVTLYDNEEVGSESAQGAQSLLTELVLRRISASCQHPTAFEEAIPKSFMISADMAHAVHPNYLDKHEENHRPLFHKGPVIKVNSKQRYASNAVSEALIREVANKVKVPLQDLMVRNDTPCGTTIGPILASRLGLRVLDLGSPQLAMHSIREMACTTGVLQTLTLFKGFFELFPSLSHNLLVD
  
Inhibitor
Name:
BDBM50008434
Synonyms:
5-Amino-2-benzyl-7-methyl-4-oxo-octanoic acid | CHEMBL140459
Type:
Small organic molecule
Emp. Form.:
C16H23NO3
Mol. Mass.:
277.3587
SMILES:
CC(C)C[C@H](N)C(=O)CC(Cc1ccccc1)C(O)=O
Structure:
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