Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50306696
Substrate
n/a
Meas. Tech.
ChEBML_1691304
Ki
4300±n/a nM
Citation
 van der Walt, MM; Terre'Blanche, G Selected C8 two-chain linkers enhance the adenosine A Eur J Med Chem 125:652-656 (2017) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
45015.65
Organism:
Rattus norvegicus (rat)
Description:
Rat A2A receptors expressed in CHO cells.
Residue:
410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
  
Inhibitor
Name:
BDBM50306696
Synonyms:
8-Benzyloxycaffeine | CHEMBL602259 | cid_223566
Type:
Small organic molecule
Emp. Form.:
C15H16N4O3
Mol. Mass.:
300.3125
SMILES:
Cn1c(OCc2ccccc2)nc2n(C)c(=O)n(C)c(=O)c12
Structure:
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