Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM50259845
Substrate
n/a
Meas. Tech.
ChEMBL_1691965 (CHEMBL4042614)
IC50
31±n/a nM
Citation
 Wei, L; Wang, J; Zhang, X; Wang, P; Zhao, Y; Li, J; Hou, T; Qu, L; Shi, L; Liang, X; Fang, Y Discovery of 2H-Chromen-2-one Derivatives as G Protein-Coupled Receptor-35 Agonists. J Med Chem 60:362-372 (2017) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM50259845
Synonyms:
CHEMBL4082281
Type:
Small organic molecule
Emp. Form.:
C10H4BrNO7
Mol. Mass.:
330.045
SMILES:
OC(=O)c1cc2cc(Br)c(O)c([N+]([O-])=O)c2oc1=O
Structure:
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