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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50260171
Substrate
n/a
Meas. Tech.
ChEBML_1692779
IC50
144±n/a nM
Citation
 Wang, YS; Li, BT; Liu, SX; Wen, ZQ; Yang, JH; Zhang, HB; Hao, XJ Anisucoumaramide, a Bioactive Coumarin from Clausena anisum-olens. J Nat Prod 80:798-804 (2017) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50260171
Synonyms:
CHEMBL4062286
Type:
Small organic molecule
Emp. Form.:
C22H23NO7
Mol. Mass.:
413.4205
SMILES:
COc1c(OC\C=C(/C)C[C@H]2OC(=O)C(CCC(N)=O)=C2)ccc2ccc(=O)oc12 |r,c:19|
Structure:
Search PDB for entries with ligand similarity: