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Target
Ubiquitin-conjugating enzyme E2 T
Ligand
BDBM50342655
Substrate
n/a
Meas. Tech.
ChEBML_1692826
Kd
1300000±n/a nM
Citation
 Morreale, FE; Bortoluzzi, A; Chaugule, VK; Arkinson, C; Walden, H; Ciulli, A Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening. J Med Chem 60:4093-4098 (2017) [PubMed]  Article 
Target
Name:
Ubiquitin-conjugating enzyme E2 T
Synonyms:
2.3.2.23 | Cell proliferation-inducing gene 50 protein | E2 ubiquitin-conjugating enzyme T | UBE2T | UBE2T_HUMAN | Ubiquitin carrier protein T | Ubiquitin-conjugating enzyme E2 T | Ubiquitin-protein ligase T
Type:
PROTEIN
Mol. Mass.:
22524.12
Organism:
Homo sapiens
Description:
ChEMBL_117368
Residue:
197
Sequence:
MQRASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPERYPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNPDDPLMADISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQKRKASQLVGIEKKFHPDV
  
Inhibitor
Name:
BDBM50342655
Synonyms:
2-ethyl-1H-indene | CHEMBL1770734
Type:
Small organic molecule
Emp. Form.:
C8H8N2S
Mol. Mass.:
164.228
SMILES:
NCc1nc2ccccc2s1
Structure:
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