Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50044714
Substrate
n/a
Meas. Tech.
ChEBML_1694030
Ki
0.550000±n/a nM
Citation
 Fanter, L; Müller, C; Schepmann, D; Bracher, F; Wünsch, B Chiral-pool synthesis of 1,2,4-trisubstituted 1,4-diazepanes as novel? Bioorg Med Chem 25:4778-4799 (2017) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50044714
Synonyms:
1-Butyl-4-[2-(3,4-dichloro-phenyl)-ethyl]-piperazine | CHEMBL310240
Type:
Small organic molecule
Emp. Form.:
C16H24Cl2N2
Mol. Mass.:
315.281
SMILES:
CCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1
Structure:
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