Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50003024
Substrate
n/a
Meas. Tech.
ChEMBL_29295 (CHEMBL640356)
Ki
3±n/a nM
Citation
 Shimada, J; Suzuki, F; Nonaka, H; Karasawa, A; Mizumoto, H; Ohno, T; Kubo, K; Ishii, A 8-(Dicyclopropylmethyl)-1,3-dipropylxanthine: a potent and selective adenosine A1 antagonist with renal protective and diuretic activities. J Med Chem 34:466-9 (1991) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
ADENOSINE A1 high | ADENOSINE A1 low | A1 adenosine receptor | ADENOSINE A1 | Adenosine Receptor A1 | AA1R_CAVPO | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36501.39
Organism:
Guinea pig
Description:
ADENOSINE A1 ADORA1 GUINEA PIG::P47745
Residue:
326
Sequence:
MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD
  
Inhibitor
Name:
BDBM50003024
Synonyms:
CHEMBL84363 | 8-Dicyclopropylmethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione | (8-(dicyclopropylmethyl)-1,3-dipropylxanthine)8-Dicyclopropylmethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C(C1CC1)C1CC1
Structure:
Search PDB for entries with ligand similarity: