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Target
Matrix protein 2
Ligand
BDBM50266584
Substrate
n/a
Meas. Tech.
ChEMBL_1701013 (CHEMBL4051995)
IC50
1900±n/a nM
Citation
 Barniol-Xicota, M; Gazzarrini, S; Torres, E; Hu, Y; Wang, J; Naesens, L; Moroni, A; Vázquez, S Slow but Steady Wins the Race: Dissimilarities among New Dual Inhibitors of the Wild-Type and the V27A Mutant M2 Channels of Influenza A Virus. J Med Chem 60:3727-3738 (2017) [PubMed]  Article 
Target
Name:
Matrix protein 2
Synonyms:
M | M2_I72A8 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11180.06
Organism:
Influenza A virus (A/Udorn/307/1972(H3N2))
Description:
ChEMBL_22
Residue:
97
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
  
Inhibitor
Name:
BDBM50266584
Synonyms:
CHEMBL4074389
Type:
Small organic molecule
Emp. Form.:
C16H27N3
Mol. Mass.:
261.4057
SMILES:
NC(=N)N1CCC(CC1)C12CC3CC(CC(C3)C1)C2 |THB:17:9:12:16.14.15,17:15:12:18.9.10,6:9:12:16.14.15,14:13:10:16.17.15,14:15:18.12.13:10|
Structure:
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