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Target
Glucagon-like peptide 1 receptor
Ligand
BDBM50266693
Substrate
n/a
Meas. Tech.
ChEMBL_1701195 (CHEMBL4052177)
EC50
0.0440±n/a nM
Citation
 Evers, A; Haack, T; Lorenz, M; Bossart, M; Elvert, R; Henkel, B; Stengelin, S; Kurz, M; Glien, M; Dudda, A; Lorenz, K; Kadereit, D; Wagner, M Design of Novel Exendin-Based Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists. J Med Chem 60:4293-4303 (2017) [PubMed]  Article 
Target
Name:
Glucagon-like peptide 1 receptor
Synonyms:
GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R_MOUSE | Glp1r
Type:
PROTEIN
Mol. Mass.:
53042.00
Organism:
Mus musculus
Description:
ChEMBL_598679
Residue:
463
Sequence:
MASTPSLLRLALLLLGAVGRAGPRPQGTTVSLSETVQKWREYRRQCQRFLTEAPLLATGLFCNRTFDDYACWPDGPPGSFVNVSCPWYLPWASSVLQGHVYRFCTAEGLWLHKDNSSLPWRDLSECEESKRGERNFPEEQLLSLYIIYTVGYALSFSALVIASAILVGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLGCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVFSEQRIFKLYLSIGWGVPLLFVIPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFIRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQMEFRKCWERWRLEHLNIQRDCSMKPLKCPTSSVSSGATVGSSVYAATCQSSYS
  
Inhibitor
Name:
BDBM50266693
Synonyms:
CHEBI:5391 | Glucagen Hypokit | Glucagon | Glucagon Emergency Kit | Glucagon Recombinant
Type:
Small organic molecule
Emp. Form.:
C153H225N43O49S
Mol. Mass.:
3482.747
SMILES:
n/a
Structure:
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