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Target
D(3) dopamine receptor
Ligand
BDBM50266969
Substrate
n/a
Meas. Tech.
ChEMBL_1701704 (CHEMBL4052937)
Ki
0.172000±n/a nM
Citation
 Michino, M; Boateng, CA; Donthamsetti, P; Yano, H; Bakare, OM; Bonifazi, A; Ellenberger, MP; Keck, TM; Kumar, V; Zhu, C; Verma, R; Deschamps, JR; Javitch, JA; Newman, AH; Shi, L Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D J Med Chem 60:580-593 (2017) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50266969
Synonyms:
CHEMBL4093656
Type:
Small organic molecule
Emp. Form.:
C24H26Cl2N4O
Mol. Mass.:
457.395
SMILES:
Clc1cccc(N2CCN(CCCCNC(=O)c3cnc4ccccc4c3)CC2)c1Cl
Structure:
Search PDB for entries with ligand similarity: