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Target
Gastrin/cholecystokinin type B receptor
Ligand
BDBM50011959
Substrate
n/a
Meas. Tech.
ChEBML_48267
IC50
370±n/a nM
Citation
 Yu, MJ; Thrasher, KJ; McCowan, JR; Mason, NR; Mendelsohn, LG Quinazolinone cholecystokinin-B receptor ligands. J Med Chem 34:1505-8 (1991) [PubMed]  Article 
Target
Name:
Gastrin/cholecystokinin type B receptor
Synonyms:
Cckbr | Cholecystokinin A | Cholecystokinin receptor | GASR_MOUSE | Gastrin/cholecystokinin type B receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49196.59
Organism:
Mouse
Description:
Cholecystokinin A CCKBR MOUSE::P56481
Residue:
453
Sequence:
MDLLKLNRSLQGPGPGSGSSLCRPGVSLLNSSSAGNLSCETPRIRGTGTRELELTIRITLYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLNLAAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTVVQPVGPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGLISRELYLGLRFDGDNDSETQSRVRNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCYVQLPRSRLEMTTLTTPTTGPGPGPRPNQAKLLAKKRVVRMLLVIVLLFFVCWLPVYSANTWRAFDGPGARRALAGAPISFIHLLSYTSACANPLVYCFMHRRFRQACLDTCARCCPRPPRARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG
  
Inhibitor
Name:
BDBM50011959
Synonyms:
3-(3-Bromo-phenyl)-2-[2-(1H-indol-3-yl)-ethyl]-3H-quinazolin-4-one | CHEMBL37887
Type:
Small organic molecule
Emp. Form.:
C24H18BrN3O
Mol. Mass.:
444.323
SMILES:
Brc1cccc(c1)-n1c(CCc2c[nH]c3ccccc23)nc2ccccc2c1=O
Structure:
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