Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50120761
Substrate
n/a
Meas. Tech.
ChEMBL_1707357 (CHEMBL4058590)
Ki
4.4±n/a nM
Citation
 Lefin, R; van der Walt, MM; Milne, PJ; Terre'Blanche, G Imidazo[1,2-?]pyridines possess adenosine A Bioorg Med Chem Lett 27:3963-3967 (2017) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM50120761
Synonyms:
CHEMBL355898 | Cyclopentanecarboxylic acid (7-methyl-2-phenyl-imidazo[1,2-a][1,3,5]triazin-4-yl)-amide
Type:
Small organic molecule
Emp. Form.:
C18H19N5O
Mol. Mass.:
321.3764
SMILES:
Cc1cn2c(NC(=O)C3CCCC3)nc(nc2n1)-c1ccccc1
Structure:
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