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Target
ELAV-like protein 1
Ligand
BDBM50270004
Substrate
n/a
Meas. Tech.
ChEMBL_1707813 (CHEMBL4059046)
Ki
>300±n/a nM
Citation
 Manzoni, L; Zucal, C; Maio, DD; D'Agostino, VG; Thongon, N; Bonomo, I; Lal, P; Miceli, M; Baj, V; Brambilla, M; Cerofolini, L; Elezgarai, S; Biasini, E; Luchinat, C; Novellino, E; Fragai, M; Marinelli, L; Provenzani, A; Seneci, P Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors. J Med Chem 61:1483-1498 (2018) [PubMed]  Article 
Target
Name:
ELAV-like protein 1
Synonyms:
ELAV1_HUMAN | ELAVL1 | HUR | Hu-antigen R
Type:
PROTEIN
Mol. Mass.:
36102.56
Organism:
Homo sapiens (Human)
Description:
ChEMBL_654855
Residue:
326
Sequence:
MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK
  
Inhibitor
Name:
BDBM50270004
Synonyms:
CHEMBL4073683
Type:
Small organic molecule
Emp. Form.:
C26H19NO4S
Mol. Mass.:
441.498
SMILES:
O=C1c2c(cn(c2C2=C(C3CCC2C=C3)C1=O)S(=O)(=O)c1ccccc1)-c1ccccc1 |c:15,t:8|
Structure:
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