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Target
Cholecystokinin receptor type A
Ligand
BDBM50013186
Substrate
n/a
Meas. Tech.
ChEMBL_50034 (CHEMBL666754)
IC50
>100000±n/a nM
Citation
 Bock, MG; DiPardo, RM; Evans, BE; Rittle, KE; Whitter, WL; Veber, DF; Freidinger, RM; Chang, RS; Chen, TB; Lotti, VJ Cholecystokinin-A receptor ligands based on the kappa-opioid agonist tifluadom. J Med Chem 33:450-5 (1990) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50013186
Synonyms:
(Diastereomer)-N-[5-(2-Fluoro-phenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl]-2-hydroxy-2-phenyl-acetamide | CHEMBL140974
Type:
Small organic molecule
Emp. Form.:
C24H22FN3O2
Mol. Mass.:
403.4488
SMILES:
OC(C(=O)NCC1CNc2ccccc2C(=N1)c1ccccc1F)c1ccccc1 |c:16|
Structure:
Search PDB for entries with ligand similarity: