Reaction Details Report a problem with these data
Target
P2Y purinoceptor 2
Ligand
BDBM50271588
Substrate
n/a
Meas. Tech.
ChEMBL_1711174 (CHEMBL4121223)
Kd
479±n/a nM
Citation
 Conroy, S; Kindon, ND; Glenn, J; Stoddart, LA; Lewis, RJ; Hill, SJ; Kellam, B; Stocks, MJ Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y J Med Chem 61:3089-3113 (2018) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 2
Synonyms:
ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2
Type:
PROTEIN
Mol. Mass.:
42299.21
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1455361
Residue:
377
Sequence:
MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL
  
Inhibitor
Name:
BDBM50271588
Synonyms:
CHEMBL4126655
Type:
Small organic molecule
Emp. Form.:
C55H55BClF2N15O5S3
Mol. Mass.:
1186.579
SMILES:
Cc1cc(C)n2c1C=C1C=CC(\C=C\c3ccc(CCC(=O)NCCCCCC(=O)NCCNC(=O)CCNc4nc5C(c6ccc(Cl)cc6C=Cc5s4)c4cn(Cc5nc(cs5)C(=O)Nc5nnn[nH]5)c(=O)[nH]c4=S)cc3)=[N+]1[B-]2(F)F |c:10,52,85,t:8|
Structure:
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