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Target
Sortase family protein
Ligand
BDBM50271717
Substrate
n/a
Meas. Tech.
ChEMBL_1711566 (CHEMBL4121615)
IC50
360±n/a nM
Citation
 Hou, X; Wang, M; Wen, Y; Ni, T; Guan, X; Lan, L; Zhang, N; Zhang, A; Yang, CG Quinone skeleton as a new class of irreversible inhibitors against Staphylococcus aureus sortase A. Bioorg Med Chem Lett 28:1864-1869 (2018) [PubMed]  Article 
Target
Name:
Sortase family protein
Synonyms:
Sortase | Sortase A (SrtA)
Type:
Enzyme
Mol. Mass.:
23546.15
Organism:
Staphylococcus aureus
Description:
n/a
Residue:
206
Sequence:
MKKWTNRLMTIAGVVLILVAAYLFAKPHIDNYLHDKDKDEKIEQYDKNVKEQASKDKKQQAKPQIPKDKSKVAGYIEIPDADIKEPVYPGPATPEQLNRGVSFAEENESLDDQNISIAGHTFIDRPNYQFTNLKAAKKGSMVYFKVGNETRKYKMTSIRDVKPTDVGVLDEQKGKDKQLTLITCDDYNEKTGVWEKRKIFVATEVK
  
Inhibitor
Name:
BDBM50271717
Synonyms:
CHEMBL4127840
Type:
Small organic molecule
Emp. Form.:
C16H16O5
Mol. Mass.:
288.2952
SMILES:
[#6]\[#6](-[#6])=[#6]/[#6]-[#6@H](-[#8])-c1cc(-[#8])c2-[#6](=O)-[#6]=[#6]-[#6](=O)-c2c1-[#8] |r,c:14|
Structure:
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