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Target
Peptidoglycan-N-acetylglucosamine deacetylase BC_1974
Ligand
BDBM50015149
Substrate
n/a
Meas. Tech.
ChEMBL_1715560 (CHEMBL4125609)
Ki
8700±n/a nM
Citation
 Balomenou, S; Koutsioulis, D; Tomatsidou, A; Tzanodaskalaki, M; Petratos, K; Bouriotis, V Polysaccharide deacetylases serve as new targets for the design of inhibitors against Bacillus anthracis and Bacillus cereus. Bioorg Med Chem 26:3845-3851 (2018) [PubMed]  Article 
Target
Name:
Peptidoglycan-N-acetylglucosamine deacetylase BC_1974
Synonyms:
3.5.1.104 | PGDA2_BACCR | Peptidoglycan GlcNAc deacetylase | Peptidoglycan-N-acetylglucosamine deacetylase BC_1974
Type:
PROTEIN
Mol. Mass.:
30683.45
Organism:
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 /NCIMB 9373 / NRRL B-3711)
Description:
ChEMBL_117859
Residue:
273
Sequence:
MEKALKIKQIVVVLIAIAAVAIGYYMFQSITSPAKAVAKQENVVQLASEQPKVEMNKTAPSRFNGKERKVAYLTFDDGPGKYTAELLNTLKQHDAKATFFLIGANVKEFPDLVKRENAEGHYVGMHSMTHNFAKLYKNGEYVNEMKEDQGLIANIIGKSPKLTRPPYGSMPGLNEGLRNKVVEGGFKVWDWTIDSLDWRYNKMPVDAAAAQIAQNVLTNATKPQEVILMHDIHPQSVAAVPAILKGLKEKGYEFEAYHEESHFPVNFWHDNRM
  
Inhibitor
Name:
BDBM50015149
Synonyms:
CHEMBL156887 | N-Hydroxy-4-naphthalen-1-yl-benzamide | N-hydroxy-4-(naphthalen-1-yl)benzamide
Type:
Small organic molecule
Emp. Form.:
C17H13NO2
Mol. Mass.:
263.2906
SMILES:
ONC(=O)c1ccc(cc1)-c1cccc2ccccc12
Structure:
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