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Target
Thromboxane A2 receptor
Ligand
BDBM50015854
Substrate
n/a
Meas. Tech.
ChEBML_209596
Kd
26±n/a nM
Citation
 Nakane, M; Reid, JA; Han, WC; Das, J; Truc, VC; Haslanger, MF; Garber, D; Harris, DN; Hedberg, A; Ogletree, ML 7-Oxabicyclo[2.2.1]heptyl carboxylic acids as thromboxane A2 antagonists: aza omega-chain analogues. J Med Chem 33:2465-76 (1990) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50015854
Synonyms:
7-{3-[(2-Heptanethioylamino-thioacetylamino)-methyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid | CHEMBL312360
Type:
Small organic molecule
Emp. Form.:
C23H38N2O3S2
Mol. Mass.:
454.689
SMILES:
CCCCCCC(=S)NCC(=S)NCC1C2CC[C@@H](O2)C1C\C=C\CCCC(O)=O
Structure:
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