Reaction Details Report a problem with these data
Target
Carbonic anhydrase 2
Ligand
BDBM50279713
Substrate
n/a
Meas. Tech.
ChEMBL_1721600 (CHEMBL4136600)
Ki
53±n/a nM
Citation
 Angeli, A; Tanini, D; Capperucci, A; Supuran, CT Synthesis of Novel Selenides Bearing Benzenesulfonamide Moieties as Carbonic Anhydrase I, II, IV, VII, and IX Inhibitors. ACS Med Chem Lett 8:1213-1217 (2017) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50279713
Synonyms:
CHEMBL4159870
Type:
Small organic molecule
Emp. Form.:
C7H6N2O2SSe
Mol. Mass.:
261.16
SMILES:
[#7]S(=O)(=O)c1ccc([Se;v2]C#N)cc1
Structure:
Search PDB for entries with ligand similarity: