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Target
D(1A) dopamine receptor
Ligand
BDBM50016003
Substrate
n/a
Meas. Tech.
ChEMBL_60352 (CHEMBL671941)
Kd
0.280000±n/a nM
Citation
 Neumeyer, JL; Baindur, N; Yuan, J; Booth, G; Seeman, P; Niznik, HB Development of a high affinity and stereoselective photoaffinity label for the D-1 dopamine receptor: synthesis and resolution of 7-[125I]iodo-8-hydroxy-3-methyl-1-(4'-azidophenyl)-2,3,4,5-tetrahydro- 1H-3-benzazepine. J Med Chem 33:521-6 (1990) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50016003
Synonyms:
CHEMBL150800 | R-[5-(4-Azido-phenyl)-8-iodo-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol]
Type:
Small organic molecule
Emp. Form.:
C17H17IN4O
Mol. Mass.:
420.2476
SMILES:
CN1CCc2cc(I)c(O)cc2[C@@H](C1)c1ccc(cc1)N=[N+]=[N-]
Structure:
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