Reaction Details Report a problem with these data
Target
Calcium-dependent protein kinase 1
Ligand
BDBM50321309
Substrate
n/a
Meas. Tech.
ChEBML_1734033
Ki
262±n/a nM
Citation
 Cabrera, DG; Horatscheck, A; Wilson, CR; Basarab, G; Eyermann, CJ; Chibale, K Plasmodial Kinase Inhibitors: License to Cure? J Med Chem 61:8061-8077 (2018) [PubMed]  Article 
Target
Name:
Calcium-dependent protein kinase 1
Synonyms:
CDPK1 | CDPK1_PLAFK | CPK1 | Calcium-dependent protein kinase 1 | PfCDPK1
Type:
PROTEIN
Mol. Mass.:
60804.87
Organism:
Plasmodium Falciparum
Description:
P62343
Residue:
524
Sequence:
MGCSQSSNVKDFKTRRSKFTNGNNYGKSGNNKNSEDLAINPGMYVRKKEGKIGESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKLRDRLGTAYYIAPEVLRKKYNEKCDVWSCGVILYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALNSKWIKKYANNINKSDQKTLCGALSNMRKFEGSQKLAQAAILFIGSKLTTLEERKELTDIFKKLDKNGDGQLDKKELIEGYNILRSFKNELGELKNVEEEVDNILKEVDFDKNGYIEYSEFISVCMDKQILFSEERLRDAFNLFDTDKSGKITKEELANLFGLTSISEQMWNEVLGEADKNKDNMIDFDEFVNMMHKICDNKSS
  
Inhibitor
Name:
BDBM50321309
Synonyms:
CHEMBL4165173
Type:
Small organic molecule
Emp. Form.:
C17H15N3O2
Mol. Mass.:
293.3199
SMILES:
Cc1ccc(cc1)C(=O)c1c(N)c(C(N)=O)c2ccccn12
Structure:
Search PDB for entries with ligand similarity: