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Target
Calcium-dependent protein kinase 1
Ligand
BDBM50321310
Substrate
n/a
Meas. Tech.
ChEBML_1734033
Ki
37±n/a nM
Citation
 Cabrera, DG; Horatscheck, A; Wilson, CR; Basarab, G; Eyermann, CJ; Chibale, K Plasmodial Kinase Inhibitors: License to Cure? J Med Chem 61:8061-8077 (2018) [PubMed]  Article 
Target
Name:
Calcium-dependent protein kinase 1
Synonyms:
CDPK1 | CDPK1_PLAFK | CPK1 | Calcium-dependent protein kinase 1 | PfCDPK1
Type:
PROTEIN
Mol. Mass.:
60804.87
Organism:
Plasmodium Falciparum
Description:
P62343
Residue:
524
Sequence:
MGCSQSSNVKDFKTRRSKFTNGNNYGKSGNNKNSEDLAINPGMYVRKKEGKIGESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKLRDRLGTAYYIAPEVLRKKYNEKCDVWSCGVILYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALNSKWIKKYANNINKSDQKTLCGALSNMRKFEGSQKLAQAAILFIGSKLTTLEERKELTDIFKKLDKNGDGQLDKKELIEGYNILRSFKNELGELKNVEEEVDNILKEVDFDKNGYIEYSEFISVCMDKQILFSEERLRDAFNLFDTDKSGKITKEELANLFGLTSISEQMWNEVLGEADKNKDNMIDFDEFVNMMHKICDNKSS
  
Inhibitor
Name:
BDBM50321310
Synonyms:
CHEMBL4175786 | US10688093, Compound 229_0226_0284 | US11701353, Compound 229_0226_0284
Type:
Small organic molecule
Emp. Form.:
C15H16N4O
Mol. Mass.:
268.3137
SMILES:
CCCNc1ccc2ncc(-c3cccc(O)c3)n2n1
Structure:
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