Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM50323317
Substrate
n/a
Meas. Tech.
ChEMBL_1734190 (CHEMBL4149726)
IC50
26±n/a nM
Citation
 Wei, L; Hou, T; Lu, C; Wang, J; Zhang, X; Fang, Y; Zhao, Y; Feng, J; Li, J; Qu, L; Piao, HL; Liang, X SAR Studies of  ACS Med Chem Lett 9:422-427 (2018) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM50323317
Synonyms:
CHEMBL4175848
Type:
Small organic molecule
Emp. Form.:
C15H12BrN5O2
Mol. Mass.:
374.192
SMILES:
COc1ccc(cc1)C(=O)Nc1cc(Br)ccc1-c1nnn[nH]1
Structure:
Search PDB for entries with ligand similarity: