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Target
Aromatic-L-amino-acid decarboxylase
Ligand
BDBM50017850
Substrate
n/a
Meas. Tech.
ChEBML_59436
IC50
50000±n/a nM
Citation
 Bäckström, R; Honkanen, E; Pippuri, A; Kairisalo, P; Pystynen, J; Heinola, K; Nissinen, E; Linden, IB; Männistö, PT; Kaakkola, S Synthesis of some novel potent and selective catechol O-methyltransferase inhibitors. J Med Chem 32:841-6 (1989) [PubMed]  Article 
Target
Name:
Aromatic-L-amino-acid decarboxylase
Synonyms:
DDC | DDC_PIG | DOPA decarboxylase
Type:
PROTEIN
Mol. Mass.:
53939.21
Organism:
Sus scrofa
Description:
ChEMBL_59433
Residue:
486
Sequence:
MNASDFRRRGKEMVDYMADYLEGIEGRQVYPDVQPGYLRPLIPATAPQEPDTFEDILQDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLQLPEAFLAGEAGEGGGVIQGSASEATLVALLAARTKVVRRLQAASPGLTQGAVLEKLVAYASDQAHSSVERAGLIGGVKLKAIPSDGKFAMRASALQEALERDKAAGLIPFFVVATLGTTSCCSFDNLLEVGPICHEEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKRRTDLTGAFKLDPVYLKHSHQGSGLITDYRHWQLPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFEAFVLQDPRFEVCAEVTLGLVCFRLKGSDGLNEALLERINSARKIHLVPCRLRGQFVLRFAICSRKVESGHVRLAWEHIRGLAAELLAAEEGKAEIKS
  
Inhibitor
Name:
BDBM50017850
Synonyms:
1-(3,4-Dihydroxy-phenyl)-2-methyl-propan-1-one | CHEMBL353187
Type:
Small organic molecule
Emp. Form.:
C10H12O3
Mol. Mass.:
180.2005
SMILES:
CC(C)C(=O)c1ccc(O)c(O)c1
Structure:
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