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Target
Prostaglandin E synthase
Ligand
BDBM50193079
Substrate
n/a
Meas. Tech.
ChEMBL_1736795 (CHEMBL4152545)
IC50
1000±n/a nM
Citation
 Khan, H; Rengasamy, KRR; Pervaiz, A; Nabavi, SM; Atanasov, AG; Kamal, MA Plant-derived mPGES-1 inhibitors or suppressors: A new emerging trend in the search for small molecules to combat inflammation. Eur J Med Chem 153:2-28 (2018) [PubMed]  Article 
Target
Name:
Prostaglandin E synthase
Synonyms:
MGST1L1 | MPGES1 | PGES | PIG12 | PTGES | PTGES_HUMAN | Prostaglandin E synthase (PGES-1) | Prostaglandin E synthase 1 (mPGES-1) | Prostaglandin E synthase-1 (PGES-1) | Prostaglandin E synthase/G/H synthase 2 | Prostaglandin E2 synthase-1 ( mPGES-1)
Type:
Protein
Mol. Mass.:
17112.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
152
Sequence:
MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
  
Inhibitor
Name:
BDBM50193079
Synonyms:
CHEBI:5834 | CHEMBL1237210
Type:
Small organic molecule
Emp. Form.:
C35H52O4
Mol. Mass.:
536.785
SMILES:
n/a
Structure:
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