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Target
Peroxidase
Ligand
BDBM50450835
Substrate
n/a
Meas. Tech.
ChEMBL_1743486 (CHEMBL4177996)
IC50
800±n/a nM
Citation
 Hroch, L; Guest, P; Benek, O; Soukup, O; Janockova, J; Dolezal, R; Kuca, K; Aitken, L; Smith, TK; Gunn-Moore, F; Zala, D; Ramsay, RR; Musilek, K Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment. Bioorg Med Chem 25:1143-1152 (2017) [PubMed]  Article 
Target
Name:
Peroxidase
Synonyms:
1.11.1.7 | Peroxidase
Type:
PROTEIN
Mol. Mass.:
31943.60
Organism:
Raphanus sativus
Description:
ChEMBL_117801
Residue:
308
Sequence:
GGSLNATFYAGTCPNASAMVRTIVQQAFQSDSRIGASLIRLHFHDCFVLGCDASILLDNSGSIISEKNAGPNANSARGFNVVDNIKTALENACPGVVSCTDVLALASQASVSLSGGPSWTVDLGRRDTLTANQAGANSSIPSPTQGLSNITSKFSAVGLNTNDLVALSGAHTFGRATCGVFSNRLFNFSGKGNPDPTLNTTLLSTLQELCPQKGRGSGSTNLDLSTPDAFDNNYFTNLQSNNGLLQSDQELFSTTGSATIAIVTSFASNQTLFFQAFAQSMINMGNISPLTGSSGEIRLDCKKTNGSG
  
Inhibitor
Name:
BDBM50450835
Synonyms:
CHEMBL4207896
Type:
Small organic molecule
Emp. Form.:
C16H15N3O2S
Mol. Mass.:
313.374
SMILES:
Oc1ccc(CNC(=S)Nc2ccc3[nH]ccc3c2)cc1O
Structure:
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