Reaction Details Report a problem with these data
Target
Eukaryotic translation initiation factor 4E
Ligand
BDBM50452630
Substrate
n/a
Meas. Tech.
ChEMBL_1748005 (CHEMBL4182515)
Kd
5900±n/a nM
Citation
 Kozarski, M; Kubacka, D; Wojtczak, BA; Kasprzyk, R; Baranowski, MR; Kowalska, J 7-Methylguanosine monophosphate analogues with 5'-(1,2,3-triazoyl) moiety: Synthesis and evaluation as the inhibitors of cNIIIB nucleotidase. Bioorg Med Chem 26:191-199 (2018) [PubMed]  Article 
Target
Name:
Eukaryotic translation initiation factor 4E
Synonyms:
IF4E_MOUSE | Eif4e
Type:
PROTEIN
Mol. Mass.:
25051.39
Organism:
Mouse
Description:
ChEMBL_627826
Residue:
217
Sequence:
MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
  
Inhibitor
Name:
BDBM50452630
Synonyms:
CHEMBL4203412
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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