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Target
P2Y purinoceptor 6
Ligand
BDBM50454137
Substrate
n/a
Meas. Tech.
ChEMBL_1752095 (CHEMBL4186855)
IC50
37±n/a nM
Citation
 Xu, P; Feng, X; Luan, H; Wang, J; Ge, R; Li, Z; Bian, J Current knowledge on the nucleotide agonists for the P2Y2 receptor. Bioorg Med Chem 26:366-375 (2018) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 6
Synonyms:
P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6
Type:
PROTEIN
Mol. Mass.:
36452.29
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1511151
Residue:
328
Sequence:
MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQRQGR
  
Inhibitor
Name:
BDBM50454137
Synonyms:
CHEMBL1321988
Type:
Small organic molecule
Emp. Form.:
C20H20N6S4
Mol. Mass.:
472.673
SMILES:
S=C=Nc1cccc(NC(=S)NCCCCNC(=S)Nc2cccc(c2)N=C=S)c1
Structure:
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