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Target
14-3-3 protein zeta/delta
Ligand
BDBM50454782
Substrate
n/a
Meas. Tech.
ChEMBL_1753374 (CHEMBL4188134)
Kd
7.3±n/a nM
Citation
 Inoue, T; Higuchi, Y; Yoneyama, T; Lin, B; Nunomura, K; Honma, Y; Kato, N Semisynthesis and biological evaluation of a cotylenin A mimic derived from fusicoccin A. Bioorg Med Chem Lett 28:646-650 (2018) [PubMed]  Article 
Target
Name:
14-3-3 protein zeta/delta
Synonyms:
14-3-3 protein zeta/delta | 1433Z_HUMAN | KCIP-1 | Protein kinase C inhibitor protein 1 | YWHAZ
Type:
PROTEIN
Mol. Mass.:
27731.18
Organism:
Homo sapiens
Description:
ChEMBL_117504
Residue:
245
Sequence:
MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN
  
Inhibitor
Name:
BDBM50454782
Synonyms:
CHEMBL4217121
Type:
Small organic molecule
Emp. Form.:
C30H48O9
Mol. Mass.:
552.6967
SMILES:
[H][C@@]12CC[C@](O)(COC)\C1=C\[C@@]1(C)CCC(C(C)C)=C1[C@@]([H])(O[C@H]1O[C@]3([H])COC(C)(C)O[C@@]3([H])[C@H](O)[C@H]1O)[C@H](O)[C@@H]2C |r,c:10,19|
Structure:
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