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Target
Estrogen-related receptor gamma
Ligand
BDBM50455423
Substrate
n/a
Meas. Tech.
ChEMBL_1754407 (CHEMBL4189167)
EC50
6000±n/a nM
Citation
 Lin, H; Doebelin, C; Patouret, R; Garcia-Ordonez, RD; Chang, MR; Dharmarajan, V; Bayona, CR; Cameron, MD; Griffin, PR; Kamenecka, TM Design, synthesis, and evaluation of simple phenol amides as ERR? agonists. Bioorg Med Chem Lett 28:1313-1319 (2018) [PubMed]  Article 
Target
Name:
Estrogen-related receptor gamma
Synonyms:
ERR gamma-2 | ERR3 | ERR3_HUMAN | ERRG2 | ESRRG | Estrogen receptor-related protein 3 | Estrogen-Related Receptor, gamma | Estrogen-related receptor gamma | KIAA0832 | NR3B3 | Nuclear receptor subfamily 3 group B member 3
Type:
PROTEIN
Mol. Mass.:
51305.00
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1501351
Residue:
458
Sequence:
MDSVELCLPESFSLHYEEELLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV
  
Inhibitor
Name:
BDBM50455423
Synonyms:
CHEMBL4211906
Type:
Small organic molecule
Emp. Form.:
C19H21N3O2
Mol. Mass.:
323.3889
SMILES:
CC(C)(C)c1ccc(\C=N\NC(=O)c2ccc(cc2)C(N)=O)cc1
Structure:
Search PDB for entries with ligand similarity: