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Target
Regulator of G-protein signaling 17
Ligand
BDBM50456401
Substrate
n/a
Meas. Tech.
ChEMBL_1756640 (CHEMBL4191648)
Kd
710000±n/a nM
Citation
 Bodle, CR; Mackie, DI; Hayes, MP; Schamp, JH; Miller, MR; Henry, MD; Doorn, JA; Houtman, JCD; James, MA; Roman, DL Natural Products Discovered in a High-Throughput Screen Identified as Inhibitors of RGS17 and as Cytostatic and Cytotoxic Agents for Lung and Prostate Cancer Cell Lines. J Nat Prod 80:1992-2000 (2017) [PubMed]  Article 
Target
Name:
Regulator of G-protein signaling 17
Synonyms:
RGS17 | RGS17_HUMAN | RGSZ2
Type:
PROTEIN
Mol. Mass.:
24356.71
Organism:
Homo sapiens
Description:
ChEMBL_118219
Residue:
210
Sequence:
MRKRQQSQNEGTPAVSQAPGNQRPNNTCCFCWCCCCSCSCLTVRNEERGENAGRPTHTTKMESIQVLEECQNPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEKARMIYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPRFLNSQIYKSFVESTAGSSSES
  
Inhibitor
Name:
BDBM50456401
Synonyms:
IRIGENOL
Type:
Small organic molecule
Emp. Form.:
C15H10O8
Mol. Mass.:
318.2351
SMILES:
Oc1cc(cc(O)c1O)-c1coc2cc(O)c(O)c(O)c2c1=O
Structure:
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