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Target
D(2) dopamine receptor
Ligand
BDBM50457572
Substrate
n/a
Meas. Tech.
ChEMBL_1760128 (CHEMBL4195136)
Ki
189±n/a nM
Citation
 Pa?czyk, K; Pytka, K; Jakubczyk, M; Rapacz, A; Sa?at, K; Furga?a, A; Siwek, A; G?uch-Lutwin, M; Grybo?, A; S?oczy?ska, K; P?kala, E; ?mudzki, P; Bucki, A; Ko?aczkowski, M; ?elaszczyk, D; Marona, H; Waszkielewicz, AM Synthesis and activity of di- or trisubstituted N-(phenoxyalkyl)- or N-{2-[2-(phenoxy)ethoxy]ethyl}piperazine derivatives on the central nervous system. Bioorg Med Chem Lett 28:2039-2049 (2018) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50457572
Synonyms:
CHEMBL4207653
Type:
Small organic molecule
Emp. Form.:
C24H36Cl2N2O3
Mol. Mass.:
471.46
SMILES:
Cl.Cl.COc1ccccc1N1CCN(CCOCCOc2c(C)cc(C)cc2C)CC1
Structure:
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