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Target
Beta-lactamase OXA-1
Ligand
BDBM50021959
Substrate
n/a
Meas. Tech.
ChEBML_40701
IC50
3200±n/a nM
Citation
 Micetich, RG; Maiti, SN; Spevak, P; Hall, TW; Yamabe, S; Ishida, N; Tanaka, M; Yamazaki, T; Nakai, A; Ogawa, K Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives. J Med Chem 30:1469-74 (1987) [PubMed]  Article 
Target
Name:
Beta-lactamase OXA-1
Synonyms:
BLO1_ECOLX | Beta-lactamase OXA-1 | Class D β-lactamase (OXA-1) | bla | oxa1
Type:
Enzyme
Mol. Mass.:
30882.83
Organism:
Escherichia coli (Enterobacteria)
Description:
Q83ZU9
Residue:
276
Sequence:
MKNTIHINFAIFLIIANIIYSSASASTDISTVASPLFEGTEGCFLLYDASTNAEIAQFNKAKCATQMAPDSTFKIALSLMAFDAEIIDQKTIFKWDKTPKGMEIWNSNHTPKTWMQFSVVWVSQEITQKIGLNKIKNYLKDFDYGNQDFSGDKERNNGLTEAWLESSLKISPEEQIQFLRKIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTGAGFTANRTLQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLNL
  
Inhibitor
Name:
BDBM50021959
Synonyms:
CHEMBL777 | MM 14151 | US9120808, Clavulanic acid potassium salt | antibiotic MM 14151 | clavulanic acid
Type:
Small organic molecule
Emp. Form.:
C8H9NO5
Mol. Mass.:
199.1608
SMILES:
OC\C=C1/O[C@@H]2CC(=O)N2[C@H]1C(O)=O |r|
Structure:
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