Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1E
Ligand
BDBM50458550
Substrate
n/a
Meas. Tech.
ChEMBL_1764105 (CHEMBL4199352)
Ki
793±n/a nM
Citation
 Kim, Y; Kim, H; Lee, J; Lee, JK; Min, SJ; Seong, J; Rhim, H; Tae, J; Lee, HJ; Choo, H Discovery of ?-Arrestin Biased Ligands of 5-HT J Med Chem 61:7218-7233 (2018) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1E
Synonyms:
5-HT-1E | 5-HT1E | 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) | 5-hydroxytryptamine receptor 1E | 5-hydroxytryptamine receptor 1E (5-HT-1E) (S31) | 5-hydroxytryptamine receptor 1E (5-HT-1E) (Serotonin receptor 1E) (5-HT1E) (S31). | 5HT1E_HUMAN | HTR1E | S31 | Serotonin (5-HT) receptor | Serotonin 1e (5-HT1e) receptor | Serotonin Receptor 1E
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41697.80
Organism:
Homo sapiens (Human)
Description:
gi_112822
Residue:
365
Sequence:
MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCREHT
  
Inhibitor
Name:
BDBM50458550
Synonyms:
CHEMBL4209274
Type:
Small organic molecule
Emp. Form.:
C13H14FN3
Mol. Mass.:
231.2688
SMILES:
Fc1ccc(cc1)-c1n[nH]c2CCNCCc12
Structure:
Search PDB for entries with ligand similarity: