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Target
Pepsin A
Ligand
BDBM50022291
Substrate
n/a
Meas. Tech.
ChEBML_154015
Ki
53±n/a nM
Citation
 Holladay, MW; Salituro, FG; Rich, DH Synthetic and enzyme inhibition studies of pepstatin analogues containing hydroxyethylene and ketomethylene dipeptide isosteres. J Med Chem 30:374-83 (1987) [PubMed]  Article 
Target
Name:
Pepsin A
Synonyms:
PEPA_PIG | PGA | Pepsin | Pepsin A precursor
Type:
Enzyme
Mol. Mass.:
41232.87
Organism:
Porcine
Description:
n/a
Residue:
385
Sequence:
MKWLLLLSLVVLSECLVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAALIGDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDSSTFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNWVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENSDGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWILGDVFIRQYYTVFDRANNKVGLAPVA
  
Inhibitor
Name:
BDBM50022291
Synonyms:
CHEMBL123741 | N-[1-(1-Hydroxy-2-{1-[(isobutyrylcarbamoyl-methyl)-carbamoyl]-ethylamino}-ethyl)-3-methyl-butyl]-3-methyl-2-(3-methyl-butyrylamino)-butyramide
Type:
Small organic molecule
Emp. Form.:
C26H48N4O6
Mol. Mass.:
512.6825
SMILES:
CC(C)C[C@H](NC(=O)C(NC(=O)CC(C)C)C(C)C)[C@@H](O)CC(C)C(=O)NCC(=O)NC(=O)C(C)C
Structure:
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