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Target
Glucagon-like peptide 1 receptor
Ligand
BDBM50266693
Substrate
n/a
Meas. Tech.
ChEMBL_1768062 (CHEMBL4220174)
EC50
2.6±n/a nM
Citation
 Knerr, PJ; Finan, B; Gelfanov, V; Perez-Tilve, D; Tschöp, MH; DiMarchi, RD Optimization of peptide-based polyagonists for treatment of diabetes and obesity. Bioorg Med Chem 26:2873-2881 (2018) [PubMed]  Article 
Target
Name:
Glucagon-like peptide 1 receptor
Synonyms:
GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R_MOUSE | Glp1r
Type:
PROTEIN
Mol. Mass.:
53042.00
Organism:
Mus musculus
Description:
ChEMBL_598679
Residue:
463
Sequence:
MASTPSLLRLALLLLGAVGRAGPRPQGTTVSLSETVQKWREYRRQCQRFLTEAPLLATGLFCNRTFDDYACWPDGPPGSFVNVSCPWYLPWASSVLQGHVYRFCTAEGLWLHKDNSSLPWRDLSECEESKRGERNFPEEQLLSLYIIYTVGYALSFSALVIASAILVGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLGCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVFSEQRIFKLYLSIGWGVPLLFVIPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFIRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQMEFRKCWERWRLEHLNIQRDCSMKPLKCPTSSVSSGATVGSSVYAATCQSSYS
  
Inhibitor
Name:
BDBM50266693
Synonyms:
CHEBI:5391 | Glucagen Hypokit | Glucagon | Glucagon Emergency Kit | Glucagon Recombinant
Type:
Small organic molecule
Emp. Form.:
C153H225N43O49S
Mol. Mass.:
3482.747
SMILES:
n/a
Structure:
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