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Target
Phenylethanolamine N-methyltransferase
Ligand
BDBM50023138
Substrate
n/a
Meas. Tech.
ChEBML_153306
Ki
176000±n/a nM
Citation
 Grunewald, GL; Ye, Q; Kieffer, L; Monn, JA Conformational requirements of substrates for activity with phenylethanolamine N-methyltransferase. J Med Chem 31:169-71 (1988) [PubMed]  Article 
Target
Name:
Phenylethanolamine N-methyltransferase
Synonyms:
Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase
Type:
Enzyme
Mol. Mass.:
30916.97
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
283
Sequence:
MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRCLAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGAFDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVREALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
  
Inhibitor
Name:
BDBM50023138
Synonyms:
1,2,3,4-Tetrahydro-isoquinolin-4-ol | CHEMBL296679
Type:
Small organic molecule
Emp. Form.:
C9H11NO
Mol. Mass.:
149.1897
SMILES:
OC1CNCc2ccccc12
Structure:
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