Reaction Details Report a problem with these data
Target
Matrix protein 2
Ligand
BDBM50462117
Substrate
n/a
Meas. Tech.
ChEMBL_1772769 (CHEMBL4229761)
IC50
31300±n/a nM
Citation
 Ramesh, R; Reddy, DS Quest for Novel Chemical Entities through Incorporation of Silicon in Drug Scaffolds. J Med Chem 61:3779-3798 (2018) [PubMed]  Article 
Target
Name:
Matrix protein 2
Synonyms:
M | M2_I72A8 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11180.06
Organism:
Influenza A virus (A/Udorn/307/1972(H3N2))
Description:
ChEMBL_22
Residue:
97
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
  
Inhibitor
Name:
BDBM50462117
Synonyms:
CHEMBL2311603
Type:
Small organic molecule
Emp. Form.:
C10H22ClNSi
Mol. Mass.:
219.827
SMILES:
Cl.[#7]-[#6]-1-[#6]-[#6][Si;v4]2([#6]-[#6]-[#6]-[#6]-[#6]2)[#6]-[#6]-1
Structure:
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