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Target
Arginase-1
Ligand
BDBM50462600
Substrate
n/a
Meas. Tech.
ChEMBL_1775774 (CHEMBL4232766)
Ki
382000±n/a nM
Citation
 Guo, X; Chen, Y; Seto, CT Rational design of novel irreversible inhibitors for human arginase. Bioorg Med Chem 26:3939-3946 (2018) [PubMed]  Article 
Target
Name:
Arginase-1
Synonyms:
ARG1 | ARGI1_HUMAN | Liver-type arginase | Type I arginase
Type:
PROTEIN
Mol. Mass.:
34737.53
Organism:
Homo sapiens (Human)
Description:
ChEMBL_978893
Residue:
322
Sequence:
MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK
  
Inhibitor
Name:
BDBM50462600
Synonyms:
CHEMBL4238387
Type:
Small organic molecule
Emp. Form.:
C11H13N3O4
Mol. Mass.:
251.2386
SMILES:
CC(=O)OC(C(O)=O)c1ccc(NC(N)=N)cc1
Structure:
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