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Target
Carnitine O-palmitoyltransferase 1, liver isoform
Ligand
BDBM50024433
Substrate
n/a
Meas. Tech.
ChEBML_216362
IC50
90±n/a nM
Citation
 Ho, W; Tarhan, O; Kiorpes, TC; Tutwiler, GF; Mohrbacher, RJ Resolution of (+/-)-2-tetradecyloxiranecarboxylic acid. Absolute configuration and chiral synthesis of the hypoglycemic R enantiomer and biological activity of enantiomers. J Med Chem 30:1094-7 (1987) [PubMed]  Article 
Target
Name:
Carnitine O-palmitoyltransferase 1, liver isoform
Synonyms:
CPT I | CPT1-L | CPT1A_RAT | CPTI-L | Carnitine O-palmitoyltransferase I, liver isoform | Carnitine palmitoyltransferase 1A | Cpt-1 | Cpt1 | Cpt1a
Type:
PROTEIN
Mol. Mass.:
88147.11
Organism:
Rattus norvegicus
Description:
ChEMBL_887445
Residue:
773
Sequence:
MAEAHQAVAFQFTVTPDGIDLRLSHEALKQICLSGLHSWKKKFIRFKNGIITGVFPANPSSWLIVVVGVISSMHAKVDPSLGMIAKISRTLDTTGRMSSQTKNIVSGVLFGTGLWVAVIMTMRYSLKVLLSYHGWMFAEHGKMSRSTKIWMAMVKVLSGRKPMLYSFQTSLPRLPVPAVKDTVSRYLESVRPLMKEEDFQRMTALAQDFAVNLGPKLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMEMLYITPTHIQAARAGNTIHAILLYRRTLDREELKPIRLLGSTIPLCSAQWERLFNTSRIPGEETDTIQHIKDSRHIVVYHRGRYFKVWLYHDGRLLRPRELEQQMQQILDDPSEPQPGEAKLAALTAADRVPWAKCRQTYFARGKNKQSLDAVEKAAFFVTLDESEQGYREEDPEASIDSYAKSLLHGRCFDRWFDKSITFVVFKNSKIGINAEHSWADAPVVGHLWEYVMATDVFQLGYSEDGHCKGDTNPNIPKPTRLQWDIPGECQEVIDASLSSASLLANDVDLHSFPFDSFGKGLIKKCRTSPDAFIQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTMESCNFVQAMMDPKSTAEQRLKLFKIACEKHQHLYRLAMTGAGIDRHLFCLYVVSKYLAVDSPFLKEVLSEPWRLSTSQTPQQQVELFDFEKNPDYVSCGGGFGPVADDGYGVSYIIVGENFIHFHISSKFSSPETDSHRFGKHLRQAMMDIITLFGLTINSKK
  
Inhibitor
Name:
BDBM50024433
Synonyms:
(+/-) 2-Tetradecyl-oxirane-2-carboxylic acid methyl ester | 2-Tetradecyl-oxirane-2-carboxylic acid methyl ester | CHEMBL12261 | Methyl palmoxirate
Type:
Small organic molecule
Emp. Form.:
C18H34O3
Mol. Mass.:
298.4608
SMILES:
CCCCCCCCCCCCCCC1(CO1)C(=O)OC
Structure:
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