Reaction Details Report a problem with these data
Target
Enoyl-(Acyl-carrier-protein) reductase II
Ligand
BDBM50464592
Substrate
n/a
Meas. Tech.
ChEMBL_1781839 (CHEMBL4253356)
IC50
2740±n/a nM
Citation
 Hu, Y; Shen, Y; Wu, X; Tu, X; Wang, GX Synthesis and biological evaluation of coumarin derivatives containing imidazole skeleton as potential antibacterial agents. Eur J Med Chem 143:958-969 (2018) [PubMed]  Article 
Target
Name:
Enoyl-(Acyl-carrier-protein) reductase II
Synonyms:
Enoyl-(Acyl-carrier-protein) reductase II | fabK
Type:
PROTEIN
Mol. Mass.:
33389.23
Organism:
Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Description:
ChEMBL_117863
Residue:
319
Sequence:
MKTRITELLNIKYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGGNAPKEVVKANIDKIKSMTDKPFGVNIMLLSPFVDDIVDLVIEEGVKVVTTGAGNPGKYMERFHEAGITVIPVVPSVALAKRMEKLGADAIITEGMEAGGHIGKLTTMTLVRQVVDAVTIPVIAAGGIADGRGAAAGFMLGADAVQVGTRFVVAKESNAHPNYKAKILKAKDIDTAVSAQVVGHPVRALKNKLVTTYSQAEKDYLAGRISINEIEELGAGALRNAVVDGDVINGSVMAGQIAGLIKSEETCQEILEDIYSGARQVILSEASRWSDL
  
Inhibitor
Name:
BDBM50464592
Synonyms:
CHEMBL4291929
Type:
Small organic molecule
Emp. Form.:
C20H24N2O3
Mol. Mass.:
340.4162
SMILES:
O=c1ccc2ccc(OCCCCCCCCn3ccnc3)cc2o1
Structure:
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