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Target
Matrix protein 2
Ligand
BDBM50465104
Substrate
n/a
Meas. Tech.
ChEMBL_1784201 (CHEMBL4255718)
IC50
24300±n/a nM
Citation
 Drakopoulos, A; Tzitzoglaki, C; McGuire, K; Hoffmann, A; Konstantinidi, A; Kolokouris, D; Ma, C; Freudenberger, K; Hutterer, J; Gauglitz, G; Wang, J; Schmidtke, M; Busath, DD; Kolocouris, A Unraveling the Binding, Proton Blockage, and Inhibition of Influenza M2 WT and S31N by Rimantadine Variants. ACS Med Chem Lett 9:198-203 (2018) [PubMed]  Article 
Target
Name:
Matrix protein 2
Synonyms:
M | M2_I72A8 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11180.06
Organism:
Influenza A virus (A/Udorn/307/1972(H3N2))
Description:
ChEMBL_22
Residue:
97
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
  
Inhibitor
Name:
BDBM50465104
Synonyms:
CHEMBL4284791
Type:
Small organic molecule
Emp. Form.:
C15H27N
Mol. Mass.:
221.3816
SMILES:
CCC(N)(CC)C12CC3CC(CC(C3)C1)C2 |TLB:9:10:14:7.8.13,THB:9:8:14:15.10.11,11:10:7:14.12.13,11:12:7:15.10.9|
Structure:
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