Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50466975
Substrate
n/a
Meas. Tech.
ChEMBL_1794681 (CHEMBL4266798)
Ki
2583±n/a nM
Citation
 Zampieri, D; Romano, M; Menegazzi, R; Mamolo, MG New piperidine-based derivatives as sigma receptor ligands. Synthesis and pharmacological evaluation. Bioorg Med Chem Lett 28:3206-3209 (2018) [PubMed]  Article 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM50466975
Synonyms:
CHEMBL4277744
Type:
Small organic molecule
Emp. Form.:
C18H26Cl2N2O
Mol. Mass.:
357.318
SMILES:
CCCN(CC1CCN(Cc2ccc(Cl)cc2Cl)CC1)C(C)=O
Structure:
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