Reaction Details Report a problem with these data
Target
Pepsin A
Ligand
BDBM50025901
Substrate
n/a
Meas. Tech.
ChEBML_154011
Ki
2.5±n/a nM
Citation
 Rich, DH Pepstatin-derived inhibitors of aspartic proteinases. A close look at an apparent transition-state analogue inhibitor. J Med Chem 28:263-73 (1985) [PubMed]  Article 
Target
Name:
Pepsin A
Synonyms:
PEPA_PIG | PGA | Pepsin | Pepsin A precursor
Type:
Enzyme
Mol. Mass.:
41232.87
Organism:
Porcine
Description:
n/a
Residue:
385
Sequence:
MKWLLLLSLVVLSECLVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAALIGDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDSSTFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNWVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENSDGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWILGDVFIRQYYTVFDRANNKVGLAPVA
  
Inhibitor
Name:
BDBM50025901
Synonyms:
4-Hydroxy-7-methyl-5-[3-methyl-2-(3-methyl-butyrylamino)-butyrylamino]-2-phenyl-octanoic acid [1-methyl-2-(4-methyl-pentanoylamino)-2-oxo-ethyl]-amide | CHEMBL90576
Type:
Small organic molecule
Emp. Form.:
C34H56N4O6
Mol. Mass.:
616.8316
SMILES:
CC(C)CCC(=O)NC(=O)[C@H](C)NC(=O)[C@@H](CC(O)[C@@H](CC(C)C)NC(=O)[C@H](NC(=O)CC(C)C)C(C)C)c1ccccc1
Structure:
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