Reaction Details Report a problem with these data
Target
Cytochrome P450 11B1, mitochondrial
Ligand
BDBM50025983
Substrate
n/a
Meas. Tech.
ChEBML_196
IC50
>100000±n/a nM
Citation
 Cross, PE; Dickinson, RP; Parry, MJ; Randall, MJ Selective thromboxane synthetase inhibitors. 1. 1-[(Aryloxy)alkyl]-1H-imidazoles. J Med Chem 28:1427-32 (1985) [PubMed]  Article 
Target
Name:
Cytochrome P450 11B1, mitochondrial
Synonyms:
C11B1_RAT | Cyp11b-1 | Cyp11b1 | Cytochrome P450 11B | Cytochrome P450 11B1
Type:
PROTEIN
Mol. Mass.:
57478.87
Organism:
Rattus norvegicus
Description:
ChEMBL_1475489
Residue:
499
Sequence:
MALRVTADVWLARPWQCLHRTRALGTTAKVAPKTLKPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQAFQELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESILPHRMPLEPWVAHRELRGLRRGVFLLNGADWRFNRLQLNPNMLSPKAIQSFVPFVDVVARDFVENLKKRMLENVHGSMSINIQSNMFNYTMEASHFVISGERLGLTGHDLKPESVTFTHALHSMFKSTTQLMFLPKSLTRWTSTRVWKEHFDSWDIISEYVTKCIKNVYRELAEGRQQSWSVISEMVAQSTLSMDAIHANSMELIAGSVDTTAISLVMTLFELARNPDVQQALRQESLAAEASIVANPQKAMSDLPLLRAALKETLRLYPVGSFVERIVHSDLVLQNYHVPAGTFVIIYLYSMGRNPAVFPRPERYMPQRWLERKRSFQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKTFQVETLRQEDMQMVFRFLLMPSSSPFLTFRPVS
  
Inhibitor
Name:
BDBM50025983
Synonyms:
CHEMBL34041 | [4-(2-Imidazol-1-yl-ethoxy)-phenoxy]-acetic acid
Type:
Small organic molecule
Emp. Form.:
C13H14N2O4
Mol. Mass.:
262.2613
SMILES:
OC(=O)COc1ccc(OCCn2ccnc2)cc1
Structure:
Search PDB for entries with ligand similarity: