Reaction Details Report a problem with these data
Target
Papain
Ligand
BDBM50026029
Substrate
n/a
Meas. Tech.
ChEBML_152507
Ki
1100±n/a nM
Citation
 Thompson, SA; Andrews, PR; Hanzlik, RP Carboxyl-modified amino acids and peptides as protease inhibitors. J Med Chem 29:104-11 (1986) [PubMed]  Article 
Target
Name:
Papain
Synonyms:
Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I
Type:
Enzyme
Mol. Mass.:
38923.01
Organism:
Carica papaya
Description:
Papain was purchased from Sigma, Germany.
Residue:
345
Sequence:
MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
  
Inhibitor
Name:
BDBM50026029
Synonyms:
2-Acetylamino-N-cyanomethyl-3-phenyl-propionamide | CHEMBL13074
Type:
Small organic molecule
Emp. Form.:
C13H15N3O2
Mol. Mass.:
245.2771
SMILES:
CC(=O)NC(Cc1ccccc1)C(=O)NCC#N
Structure:
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