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Target
Ubiquitin-conjugating enzyme E2 B
Ligand
BDBM50468268
Substrate
n/a
Meas. Tech.
ChEMBL_1799138 (CHEMBL4271430)
IC50
25±n/a nM
Citation
 Cascioferro, S; Parrino, B; Spanò, V; Carbone, A; Montalbano, A; Barraja, P; Diana, P; Cirrincione, G 1,3,5-Triazines: A promising scaffold for anticancer drugs development. Eur J Med Chem 142:523-549 (2017) [PubMed]  Article 
Target
Name:
Ubiquitin-conjugating enzyme E2 B
Synonyms:
2.3.2.23 | E2 ubiquitin-conjugating enzyme B | HR6B | RAD6 homolog B | RAD6B | UBE2B | UBE2B_HUMAN | Ubiquitin carrier protein B | Ubiquitin-conjugating enzyme E2 B | Ubiquitin-conjugating enzyme E2-17 kDa | Ubiquitin-protein ligase B | hHR6B
Type:
PROTEIN
Mol. Mass.:
17307.61
Organism:
Homo sapiens
Description:
ChEMBL_116769
Residue:
152
Sequence:
MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWNDS
  
Inhibitor
Name:
BDBM50468268
Synonyms:
CHEMBL3787660
Type:
Small organic molecule
Emp. Form.:
C17H14N6O4
Mol. Mass.:
366.3309
SMILES:
Nc1nc(COC(=O)c2ccc(cc2)[N+]([O-])=O)nc(Nc2ccccc2)n1
Structure:
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