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Target
Quorum-sensing transcriptional repressor QscR
Ligand
BDBM50468426
Substrate
n/a
Meas. Tech.
ChEMBL_1799506 (CHEMBL4271798)
IC50
>250000±n/a nM
Citation
 Boursier, ME; Manson, DE; Combs, JB; Blackwell, HE A comparative study of non-native N-acyl l-homoserine lactone analogs in two Pseudomonas aeruginosa quorum sensing receptors that share a common native ligand yet inversely regulate virulence. Bioorg Med Chem 26:5336-5342 (2018) [PubMed]  Article 
Target
Name:
Quorum-sensing transcriptional repressor QscR
Synonyms:
PhzR
Type:
PROTEIN
Mol. Mass.:
27251.33
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_466843
Residue:
237
Sequence:
MHDEREGYLEILSRITTEEEFFSLVLEICGNYGFEFFSFGARAPFPLTAPKYHFLSNYPGEWKSRYISEDYTSIDPIVRHGLLEYTPLIWNGEDFQENRFFWEEALHHGIRHGWSIPVRGKYGLISMLSLVRSSESIAATEILEKESFLLWITSMLQATFGDLLAPRIVPESNVRLTARETEMLKWTAVGKTYGEIGLILSIDQRTVKFHIVNAMRKLNSSNKAEATMKAYAIGLLN
  
Inhibitor
Name:
BDBM50468426
Synonyms:
CHEMBL3235593
Type:
Small organic molecule
Emp. Form.:
C16H26O5
Mol. Mass.:
298.3746
SMILES:
CCCCCCCCCC(=O)CC(=O)O[C@H]1CCOC1=O |r|
Structure:
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